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Medinfo http://www.doktor.ru/medinfo http://medinfo.home.ml.org E-mail: medinfo@mail.admiral.ru or medreferats@usa.net or pazufu@altern.org FidoNet 2:5030/434 Andrey Novicov - e-mail: medinfo@mail.admiral.ru


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4. .., .., .. .-.:.-1990.-.190-216.


. . , " "( , ).


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, () . , , . , . . 24 32 . 24 . : 4 , . 34-36 . . . (Grant E.,et al.,1986). A.Harcke(1972)., 28 , 28-32 - , 32 . 4-7% .

() 95 %. (Reeder J.D. et al.,1982). .

- , , - (). , . . L.A.Papile(1978):

I - ;

II - ; III - ; IV - - .

, . 26-30 77-50% , 33 - 7%(Levene M. et al.,1985). 43% . 20% . . . 72 7 . 2-3 .

(?) . . , . . 2 .

( II ) - . ,, . , (Levene M.rt al.,1985). , . -. III- IV- . . -,- . 5-6 .

- , 10 . - (Baerts W.,1985). . . - . .

, 7-10 . 26-44% , 1-2 . . 2-4 , , . 7 . . , - . 3 4- . . , 3-8 , . 60% . . 92,7%, - 94,3%. . 5 5,0 . 50 -100%. 5-7 , ( ..,1983). (Grant E.et al.,1981).

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.

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. , . , 1 , 17-20%, -15%. .

, . , - , . , , ,- ,- .

, , . "" . () . - . . 6,5%-7,5% 1700 , 16% , 34 . 8% (Levene L.et al.,1983). . . , .

., , .

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. , ( 14 ), .

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2. .., .. . .-.:.-1991.--:.343-391;:.392-422.


1. ,

. 1793 . , , , . 1918 . . .. 1928 . . ( ) , , , (Ford R.,1963).

( ) L.A.French . (1951), . L.Leksell(1956,1958), , , (,3 , ). . . ...(1969,1973) , (,, , ..)... (1966) - . ( .. .61973;Ambrose J.,1964).

1957 , (Kikushi J.et al.,1957;Adapon B.D. et al.,1965;De Vieger M.,et al.,1968). , ,, , .- , , . -. - , . . ( ..61976; .., ..,1980). - , . , , ( .. .,1991).

- , , 80- , . (Babcoch D.S.,Han B.K.,1981;Stannard M.W.,Jimenez J.F.,1982).

90 . , ,, 3- , ,, . (Schumacher R.,1984a;Allan W.C.,Philip A.G.,1985).

, , , , ., ,, ,( .., ..,1984; .. .,1984;Stannard M.W.,Jimenez J.F.,1982;Babcoch D.S.,1984;Han B.K. et al.1984;Schumacher R.,1984;Strassburg H.M. et al.,1984; Allan W.C.,Philip A.G.,1985). , (Schumacher R.,1984,1984a).

H.M.Strassburg .(1984) 4 : 1) , , , ;2) , ;3) , ;4) , , .

, ,(Frank L.M. et al.,1984;Nenenschwander S. et al.1984; Calabet A. et al.,1984).

, - , , , . (.. .,1991), (Schumacher R.,1984;Laub M.C.,Ingrisch H., 1984).


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. , 6 ( ) . . , , 1500 /c. , , :

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2.3.1.

2.3.2. 2.4. 2.5.

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2.3.2. 2.4. 2.5.

2.5.1.

2.5.2.


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- , (Babcoch D.S.,Han B.K.,1981;Stannard M.W.,Jimenez J.F.,1982).

1978 . Pape K.E.et al. 1979 . , (Grant E.G.,et al.,1980;Johnson M.L.et al.,1980).

, (Schumacher R.,1984,1984a).

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. . , . . 2 .

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======================================================

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===================== 1. ( ) ,

( 0 26 )* -----------------------------------------------------------------------

| |

| --------------------------------| | | | (IV)

| | |------------------

| |( 2 26 ) | ----------------------------------------------------| | (1) 11+2 13+3 | (2) 14+2 16+3 | (3) < 5 < 6 |

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| ---------------------------------------------------------------------- :1 - 25-50 %; 2 - 50-75%;3 - >75 %.


*- D.Voth,1983 **- Levene et al.,1985 --------------------------------------------------------------------------2.

0 15 . ------------------------------------------------------------------------

| | () | () || |-----------------------|----------|-----------|-----|----------------

| .|.|.|*| | | | | | | | -------|-----|------|-----|----|-----|----|-----|-----|-----|-----|---0 |33,0 | 35,3 |37,5 | 0 | | | | | | | 1 |35,0 | 37,2 |39,5 |1,9 | | | | | | | 2 |37,4 | 39,2 |41,5 |2.0 | | | | | | | 3 |38,7 | 40,4 |43,2 |1,2 | | | | | | | 4 |40,0 | 41,5 |44,3 |1,1 | | | | | | | 5 |41,0 | 42,5 |45,2 |1,0 | | | | | | | 6 |42,1 | 43,4 |45,9 |0,9 | | | | | | | 7 |42,9 | 44,4 |46,7 |0,8 | | | | | | | 8 |43,4 | 44,8 |47,3 |0,6 | | | | | | | 9 |43,8 | 45,3 |47,8 |0,5 | | | | | | | 10 |44,2 | 45,8 |48,2 |0,5 | | | | | | | 11 |44,6 | 46,2 |48,6 |0,4 | | | | | | | 12 |44,9 | 46,6 |48,9 |0,4 | | | | | | | 1,5| | 47,9 | | | | | | | | | 2 | | 49,0 | | | | | | | | | 3 | | 50,0 | | | | | | | | | 5 | | 51,0 | | | | | | | | | 11 | | 52,0 | | | | | | | | | 15 | | | | | | | | | | | -------------------------------------------------------------------- - ====================================================================== 3.

----------------------------------------------------------------------- | | |

| | | ------------------------------------------------------------------------


I.-


1.- , 0-3 () 2. - 2-3

"" 3. - , () ( !) 3-4

4. , 1

,

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10. , , ,-

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)

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4.

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1984; ). ----------------------------------------------------------------------- |

|---------------------------------------------------------------

| | -----------------------------------------------------------------------1-2 - ,-

, ,.

. 3-5 ,- ,,

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, .

. 6-8 , - ,-

, , ,

. , -

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** 2 **


: Wigglesworth, , , . ===================


, : , , , , , . . , . , -- .


: , .


.


1. : , , , . . , , , : , ( ). , 2 : 1 - , , (??? - - ); 2 - - .

2. : , ( ) . - - .

3. - , . , .


** 3 **


1 :

.


- (). , . . , , . , , . , , - . . , (n.caudatus,putamen,globus pallidus). , , .


2 : .


- , , , - . o ( ), , , o . o - . o Y- . , - , - , . . .


3: 4 .


- . 4- , . . - . - . - , . . , , .


** 4 **


4: .


- . o- . - . tela choridea , , . "" , . "" -, . , - , . . , .


5: glomus

.


- atrium ( ) . . , . . - . -splenium corpus callosum.


6: .


. , . , , , , - "halo".


7. .


- , 4 . - , - . , tela choridea- . tela - septum pellucidum. septum pellucidum -corpus callosum, - sulcus corpus callosum. , . clivus - . , . clivus, . , . , .


** 5 **


8.

- .


: , -. - . .


9:

.


- . - , . , . , , .. , . , . ; , , , .


10 :

.


, , . . - .


1-Richardson J.D.,Grant E.G.Scanning Techniques and Normal Anatomy.- In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage,New York, Berlin, Heidelberg, Tokyo.-1986.-P.1-24.


** 6 **



, , . .


** Cavum Septi Pellucidi, Cavum Vergae . , . , , . , , . . . , 6- . , . 100%. 2 . , , . , , . . . . . , , - cavum veli interpositi, .



- , . : . : . , .. - . , . . .



3 8 , 4,5. , , 2- .


** 7 **



, . . , . - , .


- , , , , corpus callosum ( ). , 32 . , .. .



. - . , , . - . .



. , , . - "", : , .

. , . .


** 8 **


P e r i v e n t r i c u l a r H a l o


, , . . . , , . . , . , . . , , .

2-Subramanian Siva K.N.Pathophysiology of Germinal Matrix-Related Hemorrhage and Ishemia.-In:Neurosonography of the Pre-Term Neonate/ Edited by Edward G.Grant.-Springer-Verlage,New York,Berlin,Heidel- berg,Tokyo.-1986.-P.25-32.


.

. . GMRH. , GMRH . - . GMRH, , .


G M R H

- , , , . 24 32 . . 32 . , , (! - - ), . , - , . , . .

, , , , , . , , - , .


** 9 **


:


, , , . . ( - ). - , . , , . , . , . ,, . 3-10 , ( ) , . , , , . , GMRH , , , , . , GMRH, . , . , , . , . W.J.Little 1843 "... ... , ". 100 \ Virchow Hayem 1880 . Parrot(1873) ", " " ". Banker and Larroche 1962 : " " , .. , , , .


** 10 **



, . , (). , . : , 2, ( , ) - . , . , . , . , . , , , 3 .


17 55 \100\\ 3-12 .


G M R H / P V L


, GMRH. , . (Newton ,1975 - , ; Kosmetatos N. , 1978.- " " .).


, : , , - . : , . GMRH. , . : . , GMRH/PVL : , , , , , . GMRH PVL Wegglesworth and Pape(1978)( ).


** 11 **


, . , , . . . , , . - , - \ , . . . , . . . . , . , , \ , , . , .


3.Grant E.G.Neurosonography:Germinal Matrix-Related Hemorrhage.- In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage, New York, Berlin, Heidelberg, Tokyo.-1986.-P.33-68. =========


.


. . . .


.


. , . 32 : 1 - , 2- . , . , , . 2-3 . , , .


** 12 **


-- (GMRH).


GMRH - . , -. 1975 Garrett, 1980 . , - ( CVH ), () . . :

1 CVH - .

2 - , ;

3 , .

: , , . , .

4 . 4 . GMRH: - . .


1: ()


. - (). , . . "incidental" . , . , , , . - . -, . : . - , 2 . , .


** 13 **


: 24-26 , 26-28 , . , . , ( ). . . , 10 , , . 7,5 .


II III: .


Pape and Wigglesworth(1979), 95% . 59% , , . . , , . , , . () . - . , : . , , . , . , [Wladimiroff etal.,1975]. in vitro , , , , [Wladimi-roffetal.,1975].


** 14 **


ast pattern " " [Grant]. , . , , , . ; . (.3-6, ). , . .3-6 , 3- . Y- , . , , . [Pape,1979] , , , (.3-6,). , . - ([Siegel,1983].


. . , - , . , , , . - , . , , . , , . - .


** 15 **


, . [Grant] , . Bowie et al. , , . , , . -, , . . . , , . - (.3-7). . (glomus) . , , , . . . tela choroidea. , . , , . . , . .

, . . , .

(.3-7 ). , . , ; , . , , . , (.3-7 ). , , .


** 16 **


- . , - , , , . , .....

, - . .3-7 . , , , . , . . , , , ; .3-7 .

2 : [Grant]. , , [Pape ; Papile]. 2 []. . , . 3 4 ; . , , , .


** 17 **

, - . , . . . . , . [Grant; Wicks, 1978]. . , . . , 5-6 . , , . , . " ". - : , . [Wicks, 1978]. , , . \ . , . \ ( ), . , . , . - 6 . 1-2 . . , . , . , , , . [Pape; Volpe]. - (, . , , . Luschka Magendie), . . , {86}. , . , . , , . , , . , 4 . 4- .


** 18 **


LaPlace: ( ), . , . , 4-. - . , . 4- . Dandy-Walker. - , . . 4- , . Dandy-Walker, , . 4- . , . - .

, . "" , . , , , . .

, . 7 . . 3-17 ,; 5% . [Graziani et al.,1980;Bada,1979], , [Levene].


** 19 **


, - . , , . , , . , - . , . (.3-17), , . ex vacuo, . , , [Weller, 1971], . , . , , , , . , , . [Johonson MA,1983].

, . , , . , , . , " ". .

. . . , , . Papile et al, 1980 , Mantovani et al[104] - . , ,, , . Levene and Starte [1981] , "" Papile [1980] . - (.3-18 ,).


** 20 **


, - . , , , , . , , . , . (.3-19,,). . , , . 2-3 , . , , , , . , . [Volpe, 1981; Levene]. , . , - . , . , . . , , . ( 3-20,,). , .


** 21 **


C IV: ()


. . , , [Grant]. , , [Papile].

- , , .

: , - , Rh - - . , , .. , , . - . , , . , . .


.


. , . . , , .

GMRH - . . , , , . . , , , . , , .


** 22 **


- . -, . , . , - . . , . , . , .. , . - + , .

- "-", ( , - , ). . - () , . : , , , . , - .

, , . , , . . . - . , . , - , [Grant,1986]. , " ", - . . Chinn and Filly[1983] . [Grant,1986], [Grant,1986].


** 23 **


: , - 2 . . "ringphase". : . , . . -, ( ), . \ . \ , . , . , 2 2 . , , . . 1: , , , , ; , , . . , , , . . , , .

, 15-25% . Pape and Wigglessworth[1979] , , . . , . , . , , , , .


4.Grant E.G.Neurosonography:Periventricular Leukomalacia.In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.-Springer-Verlage, New York, Berlin, Heidelberg, Tokyo.-1986.-P.69-84. =========================


** 24 **


1843 [1], Little . Virchow(1867) Parrot(1873), Banker and Larroche(1962) . Banker and Larroche - " ". , , : , Little 100 . , , . 1982-1983 , "" [8-10]. , 100 : - . , , , .

, . . . \ , . , . , . - , ex vacuo: , .

, . - . : \ . , , .


.


- . . . . . , .


** 25 **


. . , . . , . , , - . . , , . , , , . , " ". , . , . . , . , - ( ), . : , . - , . , , . .. , , + + . . , . . . . , , . . , , : . . , , , , , . . , .


** 26 **


: - Yakolev / ; - . \ , , .

, . , 25% . . . - . . , . , , . . 4 , , . , , , , . .

, , . . Levene[10] , . . . , , . , , 10 , , 20 . , , . . . , . , . , . . . , . . . 2-3 [7,11,13]. , 5 [16].


** 27 **


, . , , . , .4-14. , . . , . . , , , , . [15]. - . . , : . . " ". . . "" . , , . . [14], "", , . "" . , , .


** 28 **


25% . 75% , , . , , . . , , . , . . - , . [11,12]. , , - . , , . [17].

. : , , . , . - . - ex vacuo. , . , , . - , . , .


5.Smith Y.F.Incidence and Outcome: Germinal Matrix-Related Hemorrhage.- In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage, New York, Berlin, Heidelberg, Tokyo.-1986.-P.85-91.


** 29 **



" 4 , . , , " - Thomas Willis,1667 . . , , 300 . Gruenwald 1951 . 20% 70% [3-7]. Harcke et al [7] 1972 , 72 (23% 24 , 73% 24 72). Papipe et al. 1978, 43% , . 78% . 30 90% . 1750 , 34 . 52% . : I - 10%; II - 32%; III - 34%; IV - 24%. - 43% 3 7 . , Tstianson et al[7] , , - 2-3 , .


30% 750 92% 1251-1750 . 94% 65% .


54% 3 . , , . 80% 4 . , . , , , , 10-14 , 1981 . , . , , . 4 . . .


** 30 **


.


(, , .) : 3,6,9,12,18,24 Bayley Scales of Motor(PDI) and Mental (MDI) Development. 84 .


6.Smith Y.F.Incidence and Outcome:Periventricular Leukomalacia.- In: Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage, New York, Berlin, Heidelberg, Tokyo.-1986.- P.91-93.


5 . . 7-14 % 900-2200 ., 6 . (64%), 36% 72 . 7 , . 2 . 84% - , 92% - , ( ). 12 , , . , : . - 80%.


=====================================T======================== % =====================================+======================== 65,5 25,0 6,25 6,0 87,5 87,5 ( o ???) =====================================+======================== Bayley % =====================================+======================== MDI 75,0 PDI 87,0 L=============================================================-


W.J.Little 1843 : " ... . , , ."


7.Schellinger D.Comparison of Two Modalities: Ultrasound versus Computed Tomography.-In: Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.-Springer-Verlage, New York, Berlin, Heidelberg, Tokyo.- 1986.-P.94-113. =========================


** 31 **


,



31 41% [1,2,3]. , (43-86%) [5,18]. - 7-57% [2,69-72]. 87% . Stewart[1] , (I-II ) 15-46%, (III-IV ) - 55-69%.



- 40-60% [3,6]. 4,5-7% [4,10,73]. [11]. [12-17]. [1,3] 50-54%. - 71%. , (75%) (38%). . - ex vacuo, . , . , . , (8%) 1 (8-46%) [1,3]. . , \ .

, .


** 32 **



. ex vacuo . . . . [18-22]. [18]. 3 , . , , , , . . , . , 2-3 . [23,24].

. , , , .



: = . - . - , , .



1. ,() () : - - - - - - 2. : - - -\ (,).


()


Papile[25]. - (1 ), - (2 ), - 3 , - 4 . , , 43-86% 40-60% .


** 33 **


.


, [5,26,27,29-31], [27,32-34]. , , 90%. . , . - ( 30 ). . , , , . \ , .

: = , - . .

: , .



- 28-73%, , [2,4,6,18]. , . . , \ - . . , , , . , . ( 7-4).

.- 4. , , . , , . . () . . - \ [23,24]. : , . , [28].


** 34 **


(3-7%). , . : = , , - ; .

: .

: .

.


. , .

, . 19-24% [2,3,6,18]. . Papile . [2,7] . Flodmark[2] c, - . [6,18]. 6 17% [2,4,6]. [38,47]. [48,50,54]. , , [2]. [2] 7 1 . [55,57]. . , , . . . , . , , - [2]. , , .

>=

: , , , .

: .


** 35 **


.


[4]. 4 . : [59], [4,60], [61]. [2,6]. 9-64% [2,6,18]. [9], [9,18].

.7-6. : . , . . : , .

, ( -). . Babcock 60% Flodmark - 66%.

, . . , . . .


: >> : , .


()


- 3-18% [2,59]. . . .

Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant. - Springer-Verlage, New York, Berlin, Heidelberg, Tokyo. -1986. -116 P.


** 36 **


1-Richardson J.D.,Grant E.G.Scanning Techniques and Normal Anatomy.- In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage, New York, Berlin, Heidelberg, Tokyo. -1986.-P.1-24.


2-Subramanian Siva K.N.Pathophysiology of Germinal Matrix-Related Hemorrhage and Ishemia.-In:Neurosonography of the Pre-Term Neonate/ Edited by Edward G.Grant. -Springer-Verlage, New York, Berlin, Heidel- berg, Tokyo. -1986.-P.25-32.


3.Grant E.G.Neurosonography:Germinal Matrix-Related Hemorrhage.In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage, New York, Berlin, Heidelberg, Tokyo. -1986.-P.33-68.


4.Grant E.G.Neurosonography:Periventricular Leukomalacia.In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage,New York, Berlin, Heidelberg, Tokyo. -1986.-P.69-84.


5.Smith Y.F.Incidence and Outcome:Germinal Matrix-Related Hemorrhage.- In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage, New York, Berlin, Heidelberg, Tokyo. -1986.-P.85-91.


6.Smith Y.F.Incidence and Outcome:Periventricular Leukomalacia.In:Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant.- Springer-Verlage, New York, Berlin, Heidelberg, Tokyo. -1986.- P.91-93.


7.Schellinger D.Comparison of Two Modalities:Ultrasound versus Computed Tomography.- In: Neurosonography of the Pre-Term Neonate/Edited by Edward G.Grant. -Springer-Verlage, New York, Berlin, Heidelberg, Tokyo.- 1986.-P.94-113.


===================== 1. ( ) ,

( 0 26 )* -----------------------------------------------------------------------

| |

| --------------------------------| | | | (IV)

| | |------------------

| |( 2 26 ) | ----------------------------------------------------| | (1) 11+2 13+3 | (2) 14+2 16+3 | (3) < 5 < 6 |

| III- | L (4) < 5 < 6 | IV= ---- (5) 13+2 14+2 | D

|N()=0,15-0,25 |N(): ** | 28-29 .-30,3+4,8% 7,9+2,0 | 30-31 .-29,7+3,6% 6,1+1,9 | 32-33 .-29,5+3,4% | 34-35 .-28,9+2,9% - | 36-37 .-29,3+2,9% - | 38-40 .-27,8+3,1% ** 4,5+1,3 |

| ---------------------------------------------------------------------- :1 - 25-50 %; 2 - 50-75%;3 - >75 %.


*- D.Voth,1983 **- Levene et al.,1985 --------------------------------------------------------------------------2.

0 15 . ------------------------------------------------------------------------

| | () | () || |-----------------------|----------|-----------|-----|----------------

| .|.|.|*| | | | | | | | -------|-----|------|-----|----|-----|----|-----|-----|-----|-----|---0 |33,0 | 35,3 |37,5 | 0 | | | | | | | 1 |35,0 | 37,2 |39,5 |1,9 | | | | | | | 2 |37,4 | 39,2 |41,5 |2.0 | | | | | | | 3 |38,7 | 40,4 |43,2 |1,2 | | | | | | | 4 |40,0 | 41,5 |44,3 |1,1 | | | | | | | 5 |41,0 | 42,5 |45,2 |1,0 | | | | | | | 6 |42,1 | 43,4 |45,9 |0,9 | | | | | | | 7 |42,9 | 44,4 |46,7 |0,8 | | | | | | | 8 |43,4 | 44,8 |47,3 |0,6 | | | | | | | 9 |43,8 | 45,3 |47,8 |0,5 | | | | | | | 10 |44,2 | 45,8 |48,2 |0,5 | | | | | | | 11 |44,6 | 46,2 |48,6 |0,4 | | | | | | | 12 |44,9 | 46,6 |48,9 |0,4 | | | | | | | 1,5| | 47,9 | | | | | | | | | 2 | | 49,0 | | | | | | | | | 3 | | 50,0 | | | | | | | | | 5 | | 51,0 | | | | | | | | | 11 | | 52,0 | | | | | | | | | 15 | | | | | | | | | | | -------------------------------------------------------------------- - ====================================================================== 3.

----------------------------------------------------------------------- | | |

| | | ------------------------------------------------------------------------


I.-


1.- , 0-3 () 2. - 2-3

"" 3. - , () ( !) 3-4

4. , 1

,

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7. - "" () (1), - (1), - 3 -

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)

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1984; ). ----------------------------------------------------------------------- |

|---------------------------------------------------------------

| | -----------------------------------------------------------------------1-2 - ,-

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. 3-5 ,- ,,

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( ..,1989)

============================================

.. .(1983),..(1989) H.Portnoy .(1976), . .(1980). (), (), , , .

. . , , . , R ( ^ ) ( ^ Fl ), :

^P1 + ^P2 +^P3 ^ P ..

R= ------------------- = --------- = ----------

^Fl1 + ^Fl2 +^ Fl3 ^ Fl / ^ - , , . . 3-6 .. "" , .

. , ( .

() , V. ^ P . .


(E =---------------)

^ V

^P1,^P2 ^E1 ,^E2. E P , , - . E


EI= --- . -1, .

P

, . . () , . .

(t=35). 8+4 , 7+5 . 40 -90 .

, ..(1989). --------------------------------------------------------------------- | ||-| | -

|.| - | | | | | | | .|

| .. | -1 | ..| .// | / --------------------------------------------------------------------- 2,5-10 1,3-4 2,9+0,8 9,6+0,3 0,48+0,06* 2,9+1,3 9,9+0,5 0,44+0,3* 14,3+1,0 0,36+0,21* 9,5+3,5 25,5+12,2 0,35+0,15* ---------------------------------------------------------------------* - , , .

(Borgesen S.E.,1982;Borgessen S.E.,1984;Lorenzo A.V. et al.,1970;Lamas E. et al.,1980;Phillpon J.et al.,1976;Stein S.C.,Langfitt T.W.,1974) , 78-87% .


Medinfo http://www.doktor.ru/medinfo http://medinfo.home.ml.org E-mail: medinfo@mail.admiral.ru or medreferats@usa.net or pazufu@altern.org FidoNet 2:5030/434 Andrey Novicov - e-mail: medinfo@mail.a

 

 

 

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